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#Update: Increase in #Human #Infections with #Avian #Influenza #H7N9 Viruses During the 5th #Epidemic — #China, Oct. ‘16–Aug. 7 ‘17 (@CDCgov, edited)

Title : #Update: Increase in #Human #Infections with #Avian #Influenza #H7N9 Viruses During the 5th #Epidemic — #China, Oct. ‘16–Aug. 7 ‘17....

25 Sep 2017

Highly pathogenic #avian #influenza #H5N8, #Switzerland [infected #wildbirds] (#OIE, Sept. 25 ‘17)


Title: Highly pathogenic #avian #influenza #H5N8, #Switzerland [infected #wildbirds].

Subject: Avian Influenza, H5N8 subtype, wild birds epizootics in Switzerland.

Source: OIE, full page: (LINK).

Code: [     ]

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Highly pathogenic influenza A viruses (infection with) (non-poultry including wild birds) H5N8, Switzerland

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Information received on 22/09/2017 from Mr Hans Wyss, Chief Veterinary Officer, Schwarzenburgstrasse 161, Swiss Federal Veterinary Office, LIEBEFELD BERNE, Switzerland

  • Summary
    • Report type    Follow-up report No. 3
    • Date of start of the event    10/08/2017
    • Date of confirmation of the event    17/08/2017
    • Report date    22/09/2017
    • Date submitted to OIE    22/09/2017
    • Reason for notification    Recurrence of a listed disease
    • Date of previous occurrence    22/03/2017
    • Manifestation of disease    Clinical disease
    • Causal agent    Highly pathogenic influenza A virus
    • Serotype    H5N8
    • Nature of diagnosis    Laboratory (basic), Laboratory (advanced), Necropsy
    • This event pertains to    the whole country
  • Summary of outbreaks   
    • Total outbreaks: 1
      • Total animals affected: Species    - Susceptible    - Cases    - Deaths    - Killed and disposed of  - Slaughtered
        • Mute Swan:Cygnus olor(Anatidae) – … – 2    - 2    - 0    - 0
      • Outbreak statistics: Species    - Apparent morbidity rate    - Apparent mortality rate    - Apparent case fatality rate    - Proportion susceptible animals lost*
        • Mute Swan:Cygnus olor(Anatidae)    - **    - **    - 100.00%    - **
          • *Removed from the susceptible population through death, destruction and/or slaughter
          • **Not calculated because of missing information
  • Epidemiology
    • Source of the outbreak(s) or origin of infection   
      • Unknown or inconclusive

(...)

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Keywords: OIE; Updates; Avian Influenza; H5N8 ; Wild Birds; Switzerland.

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Highly pathogenic #avian #influenza #H5N1, #Malaysia [twenty-five #poultry #outbreaks] (#OIE, Sept. 25 ‘17)


Title: Highly pathogenic #avian #influenza #H5N1, #Malaysia.

Subject: Avian Influenza, H5N1 subtype, poultry epizootics in Malaysia.

Source: OIE, full page: (LINK).

Code: [     ]

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Highly pathogenic avian influenza H5N1, Malaysia

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Information received on 25/09/2017 from Dr Quaza Nizamuddin Bin Hassan Nizam, Deputy Director General (Veterinary Health), Department of veterinary services, Division of livestock resources & technology development, Putrajaya, Malaysia

  • Summary
    • Report type    Follow-up report No. 2 (Final report)
    • Date of start of the event    28/02/2017
    • Date of confirmation of the event    06/03/2017
    • Report date    25/09/2017
    • Date submitted to OIE    25/09/2017
    • Date event resolved    01/04/2017
    • Reason for notification    Recurrence of a listed disease
    • Date of previous occurrence    10/06/2007
    • Manifestation of disease    Clinical disease
    • Causal agent    Highly pathogenic avian influenza virus
    • Serotype    H5N1
    • Nature of diagnosis    Clinical, Laboratory (advanced)
    • This event pertains to    a defined zone within the country
  • Summary of outbreaks   
    • Total outbreaks: 25
      • Total animals affected: Species    - Susceptible    - Cases    - Deaths    - Killed and disposed of  - Slaughtered
        • Birds    - 14924    - 132    - 0    - 14924    - 0
      • Outbreak statistics: Species    - Apparent morbidity rate    - Apparent mortality rate    - Apparent case fatality rate    - Proportion susceptible animals lost*
        • Birds    - 0.88%    - 0.00%    - 0.00%    - 100.00%
          • *Removed from the susceptible population through death, destruction and/or slaughter
  • Epidemiology
    • Source of the outbreak(s) or origin of infection   
      • Unknown or inconclusive

(...)

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Keywords: OIE; Updates; Avian Influenza; H5N1 ; Poultry; Malaysia.

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#Yemen – #Cholera Response – Daily #Epidemiological #Update, September 24 2017 (@WHO EMRO, edited)


Title: #Yemen – #Cholera Response – Daily #Epidemiological #Update, September 24 2017.

Subject: Acute Watery Diarrhea and cholera outbreak in Yemen, current situation.

Source: World Health Organization (WHO), Office for the Eastern Mediterranean Region, full PDF file: (LINK).

Code: [     ]

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Yemen – Cholera Response – Daily Epidemiological Update, September 24 2017

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Keywords: WHO; Updates; Cholera; Yemen.

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#Influenza [#H1N1pdm09, #H3N2, B, #H7N9] Weekly #Report – #China - Wk 37 ‘17 – As of Sept. 25 ‘17 (CNIC, edited)


Title: #Influenza [#H1N1pdm09, #H3N2, B, #H7N9] Weekly #Report – #China - Wk 37 ‘17 – As of Sept. 25 ‘17.

Subject: Human and Animal Influenza Viruses, A & B types, current epidemiological situation in China.

Source: National Influenza Center, China, full page: (LINK).

Code: [     ]

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Influenza Weekly Report – China - Week 37 2017 – As of September 25 2017

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(All data are preliminary and may change as more reports are received)


Summary

  • During week 37, influenza activity level was very high in most provinces in southern China, and was low with increasing trend in northern China. A(H3N2) was the dominant strain nationwide.
  • Among influenza viruses antigenically characterized by CNIC since September, 2016:
    • 1508(99.6%) influenza A(H1N1)pdm09 viruses were characterized as A/California/7/2009-like;
      • 1393(92.8%) influenza A(H1N1)pdm09 viruses were characterized as A/Michigan/45/2015-like;
    • 377(40.7%) influenza A(H3N2) viruses were characterized as A/Hong Kong/4801/2014 (H3N2)(EGG)-like,
    • 902(97.3%) influenza A(H3N2) viruses were characterized as A/Hong Kong/4801/2014 (H3N2)(CELL)-like;
    • 740(90.6%) influenza B/Victoria viruses were characterized as B/Brisbane/60/2008-like;
    • 255(92.4%) influenza B/Yamagata viruses were characterized as B/Phuket/3073/2013-like.
  • Among the influenza viruses tested by CNIC for antiviral resistance analysis since September, 2016:
    • all influenza A(H1N1)pdm09 and all influenza A(H3N2) viruses were resistant to adamantine;
    • All influenza H3N2 and B viruses were sensitive to neuraminidase inhibitors.
    • All but 4 influenza A(H1N1)pdm09 viruses were sensitive to neuraminidase inhibitors.


Outbreak Surveillance

  • During week 37(Sep11-Sep17 ,2017), there were twenty-three outbreaks reported nationwide, sixteen of them were A(H3N2), two of them were B, two of them were negative, the other three have not yet identified the nature of the outbreak.


Surveillance of outpatient or emergency visits for Influenza-like Illness (ILI)

  • During week 37, the percentage of outpatient or emergency visits for ILI (ILI %) at national sentinel hospitals in southern China was 3.3%, same as the last week (3.3%), higher than the same week of 2014-2016(2.7%, 2.5%, 2.9%). (Figure 1)


Figure 2. Percentage of Visits for ILI at Sentinel Hospitals in North China (2014-2018)

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Virologic Surveillance

  • During week 37, influenza network laboratories tested 5172 specimens, of which 1092(21.1%) were positive for influenza, influenza A and influenza B viruses were 1031(94.4%) and 61(5.6%), respectively (Table 1).
  • During week 37, the percentage of specimens that were tested positive for influenza in south China was 25.0%, which was higher than the previous week (24.0%) (Figure 3).
  • During week 37, the percentage of specimens that were tested positive for influenza in north China was 8.4%, which was higher than the previous week (6.8%). (Figure 4).


Table 1 Laboratory Detections of ILI Specimens (Week 37, 2017)

[Week 37 - South China - North China – Total]

  • No. of specimens tested – 3954 – 1218 – 5172
    • No. of positive specimens (%) - 990(25.0%) - 102(8.4%) - 1092(21.1%)
      • Influenza A - 929(93.8%) - 102(100%) - 1031(94.4%)
        • A(H3N2) - 917(98.7%) - 102(100%) - 1019(98.8%)
        • A(H1N1)pdm09 - 10(1.1%) - 0(0) - 10(1.0%)
        • A (subtype not determined) - 2(0.2%) - 0(0) - 2(0.2%)
      • Influenza B - 61(6.2%) - 0(0) - 61(5.6%)
        • B (lineage not determined) - 4(6.6%) - 0(0) - 4(6.6%)
        • Victoria - 18(29.5%) - 0(0) - 18(29.5%)
        • Yamagata - 39(63.9%) - 0(0) - 39(63.9%)

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Figure 3. Influenza Positive Tests Reported by Southern Network Laboratories (Week 14, 2016–Week 37, 2017)

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Note: Analysis in this part was based on the test results of network laboratories. If it were not consistent with the results of CNIC confirmation, the results of CNIC confirmation were used.

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Figure 4. Influenza Positive Tests Reported by Northern Network Laboratories (Week 14, 2016–Week 37, 2017)

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Note: Analysis in this part was based on the result of network laboratories. If it were not consistent with the results of CNIC confirmation, the results of CNIC confirmation were used.

(…)

H7N9 case report

  • Since the notification of human infection with novel reassortant influenza A(H7N9) virus on 31 March 2013, in total 1562 laboratory-confirmed cases have been reported to WHO.
  • Among 759 cases reported in fifth wave (Since Oct 2016), 28 cases were infected with HPAI A(H7N9) virus, which have mutations in the hemagglutinin gene indicating a change to high pathogenicity in poultry.
  • These 28 cases are from Taiwan (the case had travel history to Guangdong), Guangxi, Guangdong, Hunan, Shaanxi and Hebei provinces, with illness onset date before July 2017.
  • No increased transmissibility or virulence to human case was detected in the HPAI A(H7N9) virus.

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|-- china flu report 1737 .pdf –|

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Keywords: China; Updates; H7N9; H1N1pdm09; H3N2; B; Seasonal Influenza; Avian Influenza; Human.

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Two New Confirmed #MERS #Coronavirus Cases reported by #Saudi Arabia (@SaudiMOH, Sept. 25 ‘17)


Title: Two New Confirmed MERS Coronavirus Cases reported by Saudi Arabia.

Subject: Middle East Respiratory Syndrome in Saudi Arabia, current situation.

Source: Saudi Arabia Ministry of Health, full page: (LINK).

Code: [     ]

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MOH: '2 New Confirmed Coronavirus Cases Recorded'

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9/21/2017

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New Cases Reported:

[Sex, Age, Citizenship, Resident in, Health Status, Note]

  1. Male, 48, Saudi, Hufuf, stable; *
  2. Female, 72, Saudi, Hufuf, deceased; **

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{*} Primary case (direct contact with camels);

{**} Exposure history under investigation.

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Cumulative number of confirmed cases and deaths since 2012:

  • Total No. of Cases: 1723
  • Total No. of Deaths: 698
  • Patients in treatment: 4
  • Case-Fatality Rate: 40.5%

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Keywords: Saudi Arabia; Updates; MERS-CoV.

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24 Sep 2017

#Yemen – #Cholera Response – Daily #Epidemiological #Update, September 23 2017 (@WHO EMRO, edited)


Title: #Yemen – #Cholera Response – Daily #Epidemiological #Update, September 23 2017.

Subject: Acute Watery Diarrhea and Cholera outbreak in Yemen, current situation.

Source: World Health Organization (WHO), Office for the Eastern Mediterranean Region, full PDF file: (LINK).

Code: [     ]

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Yemen – Cholera Response – Daily Epidemiological Update, September 23 2017

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Keywords: Yemen; WHO; Updates; Cholera.

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#Zika #Virus #Research #References #Library–September 24 2017 #Update, Issue No. 84


Title: #Zika #Virus #Research #References #Library–September 24 2017 #Update, Issue No. 84.

Subject: Zika Virus Infection and related complications research, weekly references library update.

Source: AMEDEO, homepage: (LINK).

Code: [     ]

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New References:

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  1. MONI MA, Lio' P.
    • Genetic Profiling and Comorbidities of Zika Infection.
      • J Infect Dis. 2017;216:703-712.
  2. ALLARD A, Althouse BM, Hebert-Dufresne L, Scarpino SV, et al.
    • The risk of sustained sexual transmission of Zika is underestimated.
      • PLoS Pathog. 2017;13:e1006633.
  3. BRAGAZZI NL, Alicino C, Trucchi C, Paganino C, et al.
    • Global reaction to the recent outbreaks of Zika virus: Insights from a Big Data analysis.
      • PLoS One. 2017;12:e0185263.
  4. SIMONIN Y, van Riel D, Van de Perre P, Rockx B, et al.
    • Differential virulence between Asian and African lineages of Zika virus.
      • PLoS Negl Trop Dis. 2017;11:e0005821.
  5. YUAN S, Zhang ZW, Li ZL.
    • Trehalose May Decrease the Transmission of Zika Virus to the Fetus by Activating Degradative Autophagy.
      • Front Cell Infect Microbiol. 2017;7:402.
  6. POLONIO CM, de Freitas CL, Zanluqui NG, Peron JPS, et al.
    • Zika virus congenital syndrome: experimental models and clinical aspects.
      • J Venom Anim Toxins Incl Trop Dis. 2017;23:41.
  7. CASTANHA PMS, Nascimento EJM, Braga C, Cordeiro MT, et al.
    • Enhancement of Zika Infection by Dengue-Specific Antibodies Does Not Alter the Production of Interleukin 6 in FcgammaRII-Expressing K562 Cells.
      • J Infect Dis. 2017;216:614-615.
  8. HUESTON L, Ramirez R, Mahalingam S.
    • Enhancement of Zika Infection by Dengue Virus-Specific Antibody Is Associated With Low Levels of Antiviral Factors.
      • J Infect Dis. 2017;216:612-614.
  9. GREGIANINI TS, Ranieri T, Favreto C, Nunes ZMA, et al.
    • Emerging arboviruses in Rio Grande do Sul, Brazil: Chikungunya and Zika outbreaks, 2014-2016.
      • Rev Med Virol. 2017 Sep 20. doi: 10.1002/rmv.1943.
  10. NEJATI J, Bueno-Mari R, Collantes F, Hanafi-Bojd AA, et al.
    • Potential Risk Areas of Aedes albopictus in South-Eastern Iran: A Vector of Dengue Fever, Zika, and Chikungunya.
      • Front Microbiol. 2017;8:1660.
  11. VAZQUEZ-CALVO A, Blazquez AB, Escribano-Romero E, Merino-Ramos T, et al.
    • Zika virus infection confers protection against West Nile virus challenge in mice.
      • Emerg Microbes Infect. 2017;6:e81.
  12. ARIS-BROSOU S, Ibeh N, Noel J.
    • Viral outbreaks involve destabilized evolutionary networks: evidence from Ebola, Influenza and Zika.
      • Sci Rep. 2017;7:11881.
  13. COLOMBO TE, Terzian ACB, Junior JPA, Parreira R, et al.
    • Zika detection: comparison of methodologies.
      • Braz J Microbiol. 2017 Aug 30. pii: S1517-8382(16)31253.
  14. TIEN WP, Lim G, Yeo G, Chiang SN, et al.
    • SYBR green-based one step quantitative real-time polymerase chain reaction assay for the detection of Zika virus in field-caught mosquitoes.
      • Parasit Vectors. 2017;10:427.
  15. DEMPSEY LA.
    • Distinct Zika responses.
      • Nat Immunol. 2017;18:1067.
  16. WIWANITKIT V.
    • Outbreak of Zika virus disease.
      • J Res Med Sci. 2017;22:89.
  17. ZHU Z, Gorman MJ, McKenzie LD, Chai JN, et al.
    • Correction: Zika virus has oncolytic activity against glioblastoma stem cells.
      • J Exp Med. 2017 Sep 15. pii: jem.2017109309122017.
  18. LIN HH, Yip BS, Huang LM, Wu SC, et al.
    • Zika virus structural biology and progress in vaccine development.
      • Biotechnol Adv. 2017 Sep 12. pii: S0734-9750(17)30115.
  19. HURTADO-VILLA P, Puerto AK, Victoria S, Gracia G, et al.
    • Raised Frequency of Microcephaly Related to Zika Virus Infection in Two Birth Defects Surveillance Systems in Bogota and Cali, Colombia.
      • Pediatr Infect Dis J. 2017;36:1017-1019.
  20. MUMTAZ N, Jimmerson LC, Bushman LR, Kiser JJ, et al.
    • Cell-line dependent antiviral activity of sofosbuvir against Zika virus.
      • Antiviral Res. 2017;146:161-163.
  21. ISKANDER J, Rose DA, Ghiya ND.
    • Science in Emergency Response at CDC: Structure and Functions.
      • Am J Public Health. 2017;107.
  22. OLYNK WIDMAR NJ, Dominick SR, Tyner WE, Ruple A, et al.
    • When is genetic modification socially acceptable? When used to advance human health through avenues other than food.
      • PLoS One. 2017;12:e0178227.
  23. BORENA W, Hofer T, Stiasny K, Aberle SW, et al.
    • No molecular or serological evidence of Zikavirus infection among healthy blood donors living in or travelling to regions where Aedes albopictus circulates.
      • PLoS One. 2017;12:e0178175.
  24. AGUIRRE-OBANDO OA, Martins AJ, Navarro-Silva MA.
    • First report of the Phe1534Cys kdr mutation in natural populations of Aedes albopictus from Brazil.
      • Parasit Vectors. 2017;10:160.
  25. MATHEUS S, de Laval F, Moua D, N'Guyen C, et al.
    • Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood.
      • Emerg Infect Dis. 2017;23.
  26. ANNAMALAI AS, Pattnaik A, Sahoo BR, Muthukrishnan E, et al.
    • Zika Virus Encoding Non-Glycosylated Envelope Protein is Attenuated and Defective in Neuroinvasion.
      • J Virol. 2017 Sep 20. pii: JVI.01348-17. doi: 10.1128/JVI.01348.
  27. SLAVOV SN, Hespanhol MR, Rodrigues ES, Levi JE, et al.
    • Zika virus RNA detection in asymptomatic blood donors during an outbreak in the northeast region of Sao Paulo State, Brazil, 2016.
      • Transfusion. 2017 Sep 16. doi: 10.1111/trf.14322.
  28. MARINI G, Guzzetta G, Rosa R, Merler S, et al.
    • First outbreak of Zika virus in the continental United States: a modelling analysis.
      • Euro Surveill. 2017;22.
  29. MOGLING R, Zeller H, Revez J, Koopmans M, et al.
    • Status, quality and specific needs of Zika virus (ZIKV) diagnostic capacity and capability in National Reference Laboratories for arboviruses in 30 EU/EEA countries, May 2016.
      • Euro Surveill. 2017;22.

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Keywords: Research; Abstracts; Zika References Library.

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#Yemen – #Cholera Response – Daily #Epidemiological #Update, September 20-22 2017 (@WHO EMRO, edited)


Title: #Yemen – #Cholera Response – Daily #Epidemiological #Update, September 20-22 2017.

Subject: Acute Watery Diarrhea and Cholera outbreak in Yemen, current situation.

Source: World Health Organization (WHO), Office for the Eastern Mediterranean Region.

Code: [     ]

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Yemen – Cholera Response – Daily Epidemiological Update, September 20-22 2017

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|—September 22 2017 Update {PDF} –|

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|—September 21 2017 Update {PDF} –|

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|—September 20 2017 Update {PDF} –|

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Keywords: WHO; Updates; Cholera; Yemen.

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23 Sep 2017

#Influenza and other #Respiratory #Viruses #Research #References #Library– September 23 2017 Issue


Title: #Influenza and other #Respiratory #Viruses #Research #References #Library– September 23 2017 Issue.

Subject: Human and Animal Influenza Viruses, other respiratory pathogens research, weekly references library update.

Source: AMEDEO, homepage: (LINK).

Code: [  R  ]

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New References:

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  1. WIDDOWSON MA, Bresee JS, Jernigan DB.
    • The Global Threat of Animal Influenza Viruses of Zoonotic Concern: Then and Now.
      • J Infect Dis. 2017;216.
  2. LIU B, Havers FP, Zhou L, Zhong H, et al.
    • Clusters of Human Infections With Avian Influenza A(H7N9) Virus in China, March 2013 to June 2015.
      • J Infect Dis. 2017;216.
  3. LIU F, Veguilla V, Gross FL, Gillis E, et al.
    • Effect of Priming With Seasonal Influenza A(H3N2) Virus on the Prevalence of Cross-Reactive Hemagglutination-Inhibition Antibodies to Swine-Origin A(H3N2) Variants.
      • J Infect Dis. 2017;216.
  4. HAVERS FP, Campbell AP, Uyeki TM, Fry AM, et al.
    • Commentary: A Historical Review of Centers for Disease Control and Prevention Antiviral Treatment and Postexposure Chemoprophylaxis Guidance for Human Infections With Novel Influenza A Viruses Associated With Severe Human Disease.
      • J Infect Dis. 2017;216.
  5. CHAKRABORTY A, Rahman M, Hossain MJ, Khan SU, et al.
    • Mild Respiratory Illness Among Young Children Caused by Highly Pathogenic Avian Influenza A (H5N1) Virus Infection in Dhaka, Bangladesh, 2011.
      • J Infect Dis. 2017;216.
  6. VENTER M, Treurnicht FK, Buys A, Tempia S, et al.
    • Risk of Human Infections With Highly Pathogenic H5N2 and Low Pathogenic H7N1 Avian Influenza Strains During Outbreaks in Ostriches in South Africa.
      • J Infect Dis. 2017;216.
  7. CREANGA A, Hang NLK, Cuong VD, Nguyen HT, et al.
    • Highly Pathogenic Avian Influenza A(H5N1) Viruses at the Animal-Human Interface in Vietnam, 2003-2010.
      • J Infect Dis. 2017;216.
  8. LEVINE MZ, Holiday C, Liu F, Jefferson S, et al.
    • Cross-Reactive Antibody Responses to Novel H5Nx Influenza Viruses Following Homologous and Heterologous Prime-Boost Vaccination with a Prepandemic Stockpiled A(H5N1) Vaccine in Humans.
      • J Infect Dis. 2017;216.
  9. GUBAREVA LV, Sleeman K, Guo Z, Yang H, et al.
    • Drug Susceptibility Evaluation of an Influenza A(H7N9) Virus by Analyzing Recombinant Neuraminidase Proteins.
      • J Infect Dis. 2017;216.
  10. PULIT-PENALOZA JA, Simpson N, Yang H, Creager HM, et al.
    • Assessment of Molecular, Antigenic, and Pathological Features of Canine Influenza A(H3N2) Viruses That Emerged in the United States.
      • J Infect Dis. 2017;216.
  11. JONES EN, Amoah S, Cao W, Sambhara S, et al.
    • An Adjuvanted A(H5N1) Subvirion Vaccine Elicits Virus-Specific Antibody Response and Improves Protection Against Lethal Influenza Viral Challenge in Mouse Model of Protein Energy Malnutrition.
      • J Infect Dis. 2017;216.
  12. BELSER JA, Creager HM, Zeng H, Maines TR, et al.
    • Pathogenesis, Transmissibility, and Tropism of a Highly Pathogenic Avian Influenza A(H7N7) Virus Associated With Human Conjunctivitis in Italy, 2013.
      • J Infect Dis. 2017;216.
  13. SKOWRONSKI DM, Chambers C, De Serres G, Sabaiduc S, et al.
    • Age-Related Differences in Influenza B Infection by Lineage in a Community-Based Sentinel System, 2010-2011 to 2015-2016, Canada.
      • J Infect Dis. 2017;216:697-702.
  14. NEUZIL KM, Chen WH.
    • Influenza Vaccines for Older Persons: Progress and Pitfalls.
      • J Infect Dis. 2017;216:397-398.
  15. ANDREW MK, Shinde V, Ye L, Hatchette T, et al.
    • The Importance of Frailty in the Assessment of Influenza Vaccine Effectiveness Against Influenza-Related Hospitalization in Elderly People.
      • J Infect Dis. 2017;216:405-414.
  16. VAN BEEK J, Veenhoven RH, Bruin JP, van Boxtel RAJ, et al.
    • Influenza-like Illness Incidence Is Not Reduced by Influenza Vaccination in a Cohort of Older Adults, Despite Effectively Reducing Laboratory-Confirmed Influenza Virus Infections.
      • J Infect Dis. 2017;216:415-424.
  17. MCELHANEY JE, McNeil SA.
    • Test-Negative Design: The Importance of Laboratory-Confirmed Illness in Estimating the Effectiveness of Influenza Vaccine in Older Adults.
      • J Infect Dis. 2017;216:399-401.
  18. KISO M, Iwatsuki-Horimoto K, Yamayoshi S, Uraki R, et al.
    • Emergence of Oseltamivir-Resistant H7N9 Influenza Viruses in Immunosuppressed Cynomolgus Macaques.
      • J Infect Dis. 2017;216:582-593.
  19. MOONEY AJ, Gabbard JD, Li Z, Dlugolenski DA, et al.
    • Vaccination with Recombinant Parainfluenza Virus 5 Expressing Neuraminidase Protects against Homologous and Heterologous Influenza Virus Challenge.
      • J Virol. 2017 Sep 20. pii: JVI.01579-17. doi: 10.1128/JVI.01579.
  20. ANDERSEN TK, Zhou F, Cox R, Bogen B, et al.
    • A DNA vaccine that targets hemagglutinin to antigen presenting cells protects mice against H7 influenza.
      • J Virol. 2017 Sep 20. pii: JVI.01340-17. doi: 10.1128/JVI.01340.
  21. NAGUIB MM, Ulrich R, Kasbohm E, Eng CLP, et al.
    • Natural reassortants between potentially zoonotic avian influenza viruses H5N1 and H9N2 from Egypt display distinct pathogenic phenotypes in experimentally infected chickens and ferrets.
      • J Virol. 2017 Sep 20. pii: JVI.01300-17. doi: 10.1128/JVI.01300.
  22. LETOURNEAU AR, Price MC, Azar MM.
    • Case 26-2017.
      • N Engl J Med. 2017;377:770-778.
  23. PRINCIPI N, Esposito S.
    • Influenza vaccine use to protect healthy children: A debated topic.
      • Vaccine. 2017 Sep 16. pii: S0264-410X(17)31232.
  24. EATON A, Lewis N, Fireman B, Hansen J, et al.
    • Birth outcomes following immunization of pregnant women with pandemic H1N1 influenza vaccine 2009-2010.
      • Vaccine. 2017 Sep 13. pii: S0264-410X(17)31180.
  25. CHAMBERS CD, Xu R, Mitchell AA.
    • Commentary on: "Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010-11 and 2011-12".
      • Vaccine. 2017;35:5323-5324.
  26. DONAHUE JG, Kieke BA, King JP, DeStefano F, et al.
    • Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010-11 and 2011-12.
      • Vaccine. 2017;35:5314-5322.
  27. WANG Y, Zhang Y, Wu J, Lin Y, et al.
    • Recombinant influenza H7 hemagglutinin containing CFLLC minidomain in the transmembrane domain showed enhanced cross-protection in mice.
      • Virus Res. 2017;242:16-23.
  28. GRIFFIN MP, Khan AA, Esser MT, Jensen K, et al.
    • Safety, Tolerability, and Pharmacokinetics of MEDI8897, the Respiratory Syncytial Virus Prefusion F-Targeting Monoclonal Antibody with an Extended Half-Life, in Healthy Adults.
      • Antimicrob Agents Chemother. 2017;61.

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Keywords: Research; Abstracts; Influenza References Library.

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22 Sep 2017

#Chikungunya #outbreak in #Rome #Region, #Italy: Ten new cases reported today, total now at 102 (Sept. 22 ‘17)


Title: Chikungunya outbreak in Rome Region: Ten new cases reported today, total now at 102.

Subject: Chikungunya fever outbreak in Rome Region, Italy.

Source: Il Messaggero, full page: (LINK). Article in Italian, edited.

Code: [     ]

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Chikungunya outbreak in Rome Region: Ten new cases reported today, total now at 102

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In a press statement released on Friday evening, the Rome Regional Government announced ten additional confirmed chikungunya fever cases. The cumulative number of cases is now 102.

Of the ten new cases, five stayed in or traveled to Anzio town – the outbreak’s epicenter – in the preceding two weeks before symptoms onset - whereas the other five cases are residents of the Rome City, without an obvious epidemiological link with Anzio.

(…)

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Keywords: Italy; Chikungunya fever.

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